A groundbreaking new therapy for modify patients T-cells potent tumor killing agents have helped three leukemia sufferers to stay cancer free for a year. T-cells or T lymphocytes are white blood cells whose main purpose is to attack and identify any body cells that are infected with viruses or harmful toxins and they are extremely necessary for a properly functioning immune system.
The study results are crucial in showing how gene transfer therapy can create specialized T-cells which protects the body form infections that attack cancerous tumors in advance cases of lymphocytic leukemia. The procedures have helped patients with little hope of survival to deter cancer and staying in remission. Senior author Carl June of the Abramson cancer Center of the University of Pennsylvania commented that, “within three weeks, the tumors had been blown away, in a way that was much more violent than we ever expected, it worked much better that we thought it would. Samples of the patients T-cells were removed and genetically customized to attack all cells that express a certain kind of protein, CD19, which includes tumor cells.
June continued is his statement in describing the “deadly killers”, “we saw at least a 1,000 fold increase in the number of modified T-cells in each of the patients. Drugs don’t do that,” said June.
It still remains a mystery as to how long this treatment may keep cancer away but they had strong hope in finding that even after months of infusion, the new cells had multiplied and were capable of continuing their seek and destroy mission against the deadly cancerous cells throughout the patient’s body.
The doctors have intend to do this study on children who are suffering from cancer and those suffering from non-Hodgkin’s lymphoma and acute lymphocytic leukemia, mesothelioma cancer cells and ovarian and pancreatic cancer cells. Chronic lymphocytic leukemia is the second most common type of adult leukemia after chronic myeloid leukemia, according to the National Cancer Institute.