NO EXPLODE good or bad

[ChrissyTtina]

Am I right or wrong....NO Explode is pretty new and also not approved, is there anything out there that would lead you to believe that its long term effects may be very very bad???

[krembles]

What is the world are you talking about?

[tee]

Welcome to the board. Why would you think it would have negative long term health effects? Also, who is supposed to "Approve" it?

[roccodart440]

WTF?

NOExplode isn't that "new" it's newer. THers nothing in it that is a health hazzard especially long term except maybe the caffeine.

As far as efficiency? I used NOexplode and I've tried the Fizogen Mid cyle. The Fizogen works better, gives you better gains and doens't taper in effect as quickly as NOExplode in the long run. WHat I mean is with NOexplode after you use it for a week or so looses it's effect everytimre you take whereas the fizogen works everytime in the short run and the long term steady gains never ended. I got sick of the smell and tast and bored of taking the Fizogen. It's the only reason I stopped.

[solcraft]

WTF?

NOExplode isn't that "new" it's newer. THers nothing in it that is a health hazzard especially long term except maybe the caffine

it never ceaces to amaze me how people will just make comments like this with no research or anything to back up thier assumption that a supplement or product is "safe". then give out advice like they know what they are talking about. i don't mean this as a dis to you -just education bro-
roccodart, you should do some reading on what you are promoting before you tout its effectiveness, or safeness.just because you see a product in all the muscle mags doesnt mean it is worth a shit. as far as noexplode is concerned, the caffine is the least of the health hazzards. it is the long term health hazzards you should be concerned with. not to mention the incredible waste of money this product, and products like this truly are. price the main ingredients and you will see that you are paying for some very flashy packaging, with little value as far as muscle building or retention.
and i don't just throw things out there with no research to back it up-

By David Tolson...

Sure brother, NO2 is made by most supplement companies now, but I would avoid it and heres why:

Might as well go for regular ol creatine. ...

The effectiveness of A-AKG in increasing NO
I did some research on this as well. AKG is metabolized into glutamate, which is then metabolized into l-glutamine (2). But this does not mean that it is nothing more than l-glutamine, remember that glutamate is the intermediary step.

Coincidentally... while researching fibromyaglia, I found that many cases of FM can be cured by eliminating MSG from the diet. MSG metabolizes to glutamate, which is an "excitotoxin," meaning it activates the NMDA receptors to the point of neural damage. And guess what... that leads to excessive nitric oxide levels (1). In other words, AKG does not work synergistically with arginine per se. It operates via a seperate mechanism to increase NO levels, and a potentially dangerous one. Ornithine-AKG has the same effect (2). I couldn't find any human studies regarding the safety of AKG, but I did find in many places (none of them "legitimate" though) that no such studies exist.

In light of this, I have developed a theory. The theory is that in NO2 and related products, the AKG is the important part and the arginine is just there for show (as opposed to what many people who criticize the products think, which is that the AKG is the useless part). I have been trying to find evidence to support this by finding references that say dietary arginine does not raise NO levels. What I've found so far:

-Every time NO levels go up, there is an increase in arginine disposal, which would imply that the body only uses what it needs based on other controlling mechanisms (such as the NMDA part of the brain) (3).
-Two analogues of arginine, ADMA and L-NMMA, are formed when there are excess amounts of arginine in cells. Both of these analogues inhibit the synthesis of more nitric oxide. In other words, whenever the body has enough arginine, it sends a message to slow production of nitric oxide.
-The only studies I found showing that administration of arginine increased NO levels was in cases of deficiency.

If anybody has more references on this, please let me know.

David

1. Smith J. D., Terpening C. M., Schmidt S. O. F., Gums J. G. Relief of fibromyalgia symptoms following discontinuation of dietary excitotoxins. Ann Pharmacotherapy 2001;35:702-706.
2. Le Boucher J et al., Enteral administration of ornithine alpha-ketoglutarate or arginine alpha-ketoglutarate: a comparative study of their effects on glutamine pools in burn-injured rats, Crit Care Med 1997 Feb;25(2):293-8
3. Bruins MJ, Lamers WH, Meijer AJ, Soeters PB, Deutz NE. In vivo measurement of nitric oxide production in porcine gut, liver and muscle during hyperdynamic endotoxaemia. Br J Pharmacol 2002 Dec;137(8):1225-36


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NO2 Exposed - Part 2


There are now quite a few supplements out there that claim to increase nitric oxide levels in the body. Examples include NO2, Nitro AKG, and NOX2. For the moment, I'm going to assume that these substances increase nitric oxide levels above the normal levels found in an otherwise healthy individual. What would this do?

The main functions of NO in various systems are listed here:

Immune system: Macrophages produce NO to kill target cells because it is cytotoxic. It disrupts the Kreb's cycle, DNA synthesis, and mitochondrial function, making it a very effective cell killer.

Nervous system: Acts as a neurotransmitter and regulates apoptosis (cell death) in neurons. NO is also correlated with the excitation of NMDA receptors.

Circulatory system: NO stimulates the production of pro-inflammatory compounds (specifically, eiconosoids), and other pro-inflammatory compounds are known to stimulate the production of NO. NO is also a vasiodilator.

I could find no evidence or reasons to believe than NO will cause gains in strength. If anybody has any, please let me know. The "pump" effect that many report could be due to vasiodilation (assuming the supplement increases NO levels).

Of prime importance here is the function of NO in the immune and nervous systems. I'll try to dumb this down as much as I can. O2-, or super-oxide, is the most prevalent oxidant in the body. That means: it's bad for you. Luckily, it is not very stable. ONOO- (peroxynitrite) is another oxidant, but is much more stable. So while super-oxide can do damage, peroxynitrite can do much more. On top of that, it can pass freely through cell membranes. When super-oxide reacts with NO, it forms peroxynitrate.

In the immune system, macrophages kill target bacteria and tumor cells through a targetted release of NO, which reacts with super-oxide to form peroxynitrite. This peroxynitrite then kills the targetted bacterium or cancer cell. So basically your immune system's defense is: poison the target cell.

This point should not be taken lightly. The more NO there is in your bloodstream, the more NO reacts with super-oxide to form peroxynitrite. But in this case, it's not a controlled response like immune response or apoptosis in neurons.

Now here's what makes the situation even worse. Under normal circumstances, the amount of NO in your system is closely mediated. There are three types of NOS (nitric oxide synthase, which produces NO in the body), and each responds to different things (such as the amount of calcium in cells). But like I said, let's assume that you can increase NO levels above normal. As described above, this causes peroxynitrite levels to go up. But peroxynitrate acts through six mechanisms to increase the levels of nitric oxide and super-oxide even more - which in turn produces more peroxynitrite. This is why peroxynitrate is such a potent cell killer; it reproduces itself. Once peroxynitrite levels hit a certain point, they will be self-sustaining (1).

To summarize: when NO levels hit a certain point, there can be a permanent increase in peroxynitrite levels. This, in turn, increases your chances of a variety of ailments. Some are described below.

Fibromyalgia (FM): Causes pain in all the fibrous tissues in the body, including muscles, ligaments, and tendons. The pain can be incapacitating. It is also associated with oxidative damage. Studies show excessive levels of nitric oxide and peroxynitrite as well as excessive activity in the NMDA system (in the brain) in FM patients. Nitric oxide stimulates nociceptors, neurons that cause the sensation of pain, and peroxynitrite does as well, which could quite possibly be the primary mechanism of action in this illness (2).

Chronic Fatigue Syndrome (CFS):Incapacitating fatigue, joint pain (similar to FM pain), inability to concentrate, and flu-like symptoms. Like FM, this is associated with elevated levels of nitric oxide.

Multiple Chemical Sensitivity (MCS): A controversial condition where people have negative responses to sub-toxic levels of various chemicals. Also associated with high nitric oxide levels.

All three of these conditions are chronic, and all three of them are related. They can all develop over a long period of time. What's even more surprising is all three of them are treated with vitamin B12 injections. Coincidentally, B12 is a potent nitric oxide scavenger (3).

I know that in my case, at least, I am no longer going to search for ways of artifically increasing nitric oxide levels. There's no evidence that it increases muscle strength, and there's no evidence that the "pump" is due to anything other than vasiodilation. What's more, there's plenty of evidence that messing with your body's normal balance of NO will do more harm than good.

David

1. Pall ML. Elevated, sustained peroxynitrite levels as the cause of chronic fatigue syndrome. Medical Hypotheses 2000;54:115-125.
2. Pall M. L. Common etiology of posttraumatic stress disorder, fibromyalgia, chronic fatigue syndrome and multiple chemical sensitivity via elevated nitric oxide/peroxynitrite. Med Hypoth 2001;57:139-145.
3. Pall M. L. Cobalamin used in chronic fatigue syndrome therapy is a nitric oxide scavenger. J Chronic Fatigue Syndr 2001:8(2);39-44.

From shpongled

L-Arginine's function is a precursor to NO. It is not selectively used by iNOS, eNOS, or nNOS, to my knowledge. Since it enters the bloodstream during digestion, perhaps it is primarily utilized by eNOS. Either way, we can be sure that arginine does not increase NOS, just makes more of the NO precursor available to it.

My purpose in this post is to explore ways in which alpha-ketoglutarate (AKG) might increase NO production.

The first step is figuring out as much as I can - or what's relevant at least - about where AKG comes from and it's action on the body. To avoid confusing people too much, O-AKG and OKG are both names for ornithine alpha-ketoglutarate, and A-AKG is arginine alpha-ketoglutarate. To the best of my knowledge arginine and orginine are "carriers" and the body breaks them down separately into the amino acid and AKG. If anyone knows more about this, please let us know.

AKG is, in fact, naturally found in the body as an intermediate in the Kreb's cycle. But like nitric oxide, that does not mean an artifically large amount is a good thing. The body makes AKG when it needs it, where it needs it by itself. In some cases there is deficiency, but rarely in the general population.

AKG is the carbon skeleton of the amino acid glutamate. The rate at which AKG metabolizes into glutamate is relatively slow, so AKG could have an effect on the body independent of glutamate. A new study I found shows that AKG has a unique effect on the body. Some quotes from the study:

"OKG is usually recognized as generating glutamine, arginine and polyamines.... Inhibition of glutamine synthetase showed that glutamine production was not involved in the action of OKG. The use of S-methylthiourea and difluoromethylornithine demonstrated that OKG modulated the respiratory burst via nitric oxide (NO*) and polyamine generation. Moreover, OKG stimulated PMN migration via NO*, but arginine administration failed to reproduce this effect. These data suggest that OKG (or its metabolites) and arginine are channelled differently in PMNs. This hypothesis deserves further study."

As you can see, the effects of dietary AKG, the compound in all these NO products, is barely understood. Only a few things about it are known. It could have a variety of positive and negative benefits in different doses. So, since we know AKG breaks down into glutamate for sure, there are two possible compounds that exhibit toxic effects:

-AKG
-Glutamate

We know that excess amounts of glutamate can do quite a bit of damage to begin with. So we'll take a look at that first.

Glutamate, at first glance, seems like it couldn't be toxic at all. It's the most common excitatory neurotransmittor, and essential for brain function. Another name for glutamate is glutamic acid - a nonessential amino acid. They are essentially the same, although glutamate technically is an anion of glutamic acid. whey protein is about 10% L-glutamic acid. Since L-glutamic acid is nonessential, it is very likely that additional supplementation can do more harm than good. A VERY interesting read on glutamine, glutamate etc. is here:

http://www.dietsexercise.com/glutamine-text4.htm
From this text:

quote:
--------------------------------------------------------------------------------

Glutamate is our chief excitatory neurotransmitter. It is essential for learning and both short-term and long-term memory. Problems arise only if the normal process of glutamate removal and conversion to glutamine malfunctions and an excess of this excitatory neurotransmitter builds up in the synaptic junctions. Excess glutamate causes excessive influx of calcium ions into the neurons causing excitotoxicity and ultimately even death of the neurons. It also destroys glutathione - a crucial brain-protective antioxidant. Low levels of brain glutathione are associated with neurodegenerative disorders. Glutathione depletion further leads to neuronal death.
Under what conditions do we see excess levels of glutamate at the synapses? Not surprisingly, we see evidence of damage associated with excess glutamate in Alzheimer's, AIDS patients, and cancer patients. The AIDS virus inhibits glutamate uptake by the glia. According to one hypothesis, cancer starts with brain dysfunction and in those who have suffered a severe brain injury. Very high fever or artificially induced hyperthermia can also result in excess glutamate release, leading to seizures.
--------------------------------------------------------------------------------


Over-stimulation of glutamate receptors is ALSO associated with Lou Gehrig's Disease and epilepsy. This is quite a list of conditions so far.

Confused at first (because it seems dietary glutamate doesn't have much of an effect on brain levels), I remembered that the glutamate from MSG was specifically implicated in CFS/FM etc. I stumbled upon this (warning: politically motivated?) website: http://www.truthinlabeling.org/msgfacts.html. A quote: "MSG-sensitivity is a sensitivity to free glutamic acid that occurs in food as a consequence of manufacture. All protein contains glutamic acid bound in it, but only when glutamic acid has been freed from protein before it is eaten do people have MSG-sensitivity reactions, provided that they ingest amounts that exceed their individual tolerance levels. Some unadulterated protein may have minute amounts of free glutamic acid associated with it, but MSG-sensitive people do not generally report adverse reactions following ingestion of unadulterated protein."

Another: "The names of most other MSG-containing ingredients won't give consumers even a clue to the fact that the ingredients contain MSG. "Monosodium glutamate," "monopotassium glutamate," "autolyzed yeast," "hydrolyzed soy protein," and "sodium caseinate," are examples of ingredients that always contain MSG." It seems hydrolyzed protein sources are especially implicated, which makes sense because they contain aminos in their free form.

What I think, at this point, is that glutamic acid in a protein source is harmless. However, free form glutamic acid can somehow disrupt the levels of glutamate in the brain, causing over-excitation of neurotransmittors. This might be a good reason why hydrolyzed protein sources might not be so great after all. So basically I've come full circle: back to AKG. If it's arginine-AKG or ornithine-AKG, I would logically think it wouldn't qualify as "free form." So, back to looking at how these substances metabolize.

Remember that above I stated that OKG metabolizes into glutamate, but doesn't seem to effect l-glutamine levels. This is where the pieces start to fit together. Another quote from the l-glutamine article (2):

quote:
--------------------------------------------------------------------------------
However, the use of glutamine as a free amino acid has never been associated with any form of brain damage. glutamine is in fact abundantly produced in the brain as a vital defense against ammonia and also against excess glutamate. The main defense against glutamate excitotoxicity is the synthesis of glutamine by cells called the glia, or more specifically, astroglia or astrocytes. They are most abundant type of cell in the central nervous system exhibiting high amounts of glutamine synthase. The healthy brain is very well equipped to deal with glutamate. But, when the brain is damaged due to stroke or injury or the accumulation of various neurotoxins including certain drugs, the stage is set for glial dysfunction and hence for glutamate excitotoxicity.
--------------------------------------------------------------------------------


So... here's where the unique effects of AKG come into play. Normally, excess glutamate is readily metabolized into glutamine, which protects against the neurotoxicity. But somehow, O-AKG (and A-AKG as well I'm assuming) increase glutamate levels without the corresponding increase in glutamine. Through some mechanism, they bypass the body's primary defense against excess glutamate.

This is how glutamate levels are increased in the brain. This is universally accepted as a bad thing. This is how AKG can excite the NMDA receptors, leading to excess levels of nitric oxide. In a future post, I'll look at that more closely. I think it's safe to say, at this point, that this can be taken as a given:

-Arginine AKG and Ornithine AKG increase levels of glutamate above normal. Consumption of glutamic acid in protein or l-glutamine will not do this. Consumption of free-form glutamic acid *may* do this, but that issue is no longer relevant.
-The above-normal levels of glutamate would explain the excess amount of nitric oxide when these supplements are taken.

That's all for now. Sorry if this is disjointed, I typed as I researched and then went back and did a small amount of editing.

David

1. Moinard C et al., Effects of ornithine 2-oxoglutarate* on neutrophils in stressed rats: evidence for the involvement of nitric oxide and polyamines. Clin Sci (Lond) Mar 2002; 102(3):287-95 (*2-oxoglutarate = OKG)
2. http://www.dietsexercise.com/glutamine-text4.htm

[roccodart440]

Solcraft wrote "it never ceaces to amaze me how people will just make comments like this with no research or anything to back up thier assumption that a supplement or product is "safe". then give out advice like they know what they are talking about."

Well I've done much reading on both creatine and NO2. I've tried both solo and stacked as have my W/O partners and the info I provided has also been supported and confirmed by not 1, not 2 but 3 of my physisians.

Solcraft also wrote "you should do some reading on what you are promoting before you tout its effectiveness, or safeness.just because you see a product in all the muscle mags doesnt mean it is worth a shit."

Well i've read and i've tried it and my physision uses it himself. I also said I DON't like and DO NOT tout NOExplode. DId you read my post?

NO2 IMO and IME is not a waste of money. I have experimented with it over the past year as have my w/o partners and all yes ALL of us are at an all time, lifetime high. If nothing more than a vascular pump and w/o enhancer it is worth the money. No gyno, no rage, no acne, no hormonal shutdowns, testicular atropy, hair loss or any of the above. Hell it's worth the money even if you get a placebo effect.

TO conclude I read a whooel book and did some internet reading on stacking the two supplents (creatine and NO2) and that is the only time I got any gains from them. Creatine by itself has proven several times over to not work for me. So my post was and is a result of personal trial and experience plus 2 other guys trial and experience, and several hours of reading multiplyed by theirs as well.

I hate defending myself on discussion threads but I felt it was neccessary. If you'd like me to remove my earlier post after reading this one I will gladly do so. This is one board I don't want to get a bad rap or piss anybody off in.

roccodart440

[solcraft]

i can definately respect your position. like i said, i'm not trying to dis or flame you in any way, however the effectiveness of no2 products (aside frome the pump) is minimal. the ingredients are a fraction of the cost when bought seperately. i just get tired hearing people attribute thier gains (and it sounds like you've had some good gains) to using no2 products with no real reasearch to back them up. i know personal experience is valuable- you have to know what works for you- but it does not take the place of scientific evidence. my point is threefold- 1-no2 products are cheaper to put together yourself; 2-no2 products long term effects are probably detrimental to your health(short term seems OK);3- the cost far out wieghs the value of no2 use.
by all means if you have any research to back up that no2 products are safe and/or effective please quote it, and i will be corrected. and yes, i do aggree that noexplode is crap....

[roccodart440]

Thanks. I can't scientificly back up my gains but I can attest to the pump anmd of course what is scientificly known about the two supps.

As for long term safety? IMO both of these supps should be cycled not used steaddily or just used sporaticly for the boost one gets on them.

My favorite is fizogen mid cycle.

Mid Cycle: High Tech Creatine and Nitric Oxide Generating Fusion
MID CYCLE is a scientifically developed “muscle building bridge” designed to be utilized in the MID portion of The Continuous Cycle. This formulation is a high-tech creatine and nitric oxide generating fusion that may drive creatine and nitric oxide into muscle cells. Although effective when used on its own, MID CYCLE was uniquely developed to amplify the effects of ON CYCLE and OFF CYCLE by enhancing nutrient uptake, increasing cell-signaling vasodilation and promoting improved muscle torque and intercellular energy levels. MID CYCLE may enhance creatine storage in muscle cells, which may lead to increased size and strength in athletes.


Rapid muscle augmentation, growth and strength increases experienced by users
within 2 weeks of use… guaranteed!

Results are even further multiplied when stacked within the recommended dosing structure below!

THE CONTINUOUS CYCLE™



Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8
On Cycle 6 Caps/day 6 Caps/day 6 Caps/day 6 Caps/day
Mid Cycle 2 scoops/day 2 scoops/day 2 scoops/day 2 scoops/day
Off Cycle 3 caps/day 3 caps/day 3 caps/day 3 caps/day

PH-Fuse3 – 10,000 mg
A high-tech creatine transport system designed to fuel massive ATP production in muscle cells at a continuous and extremely high rate of speed. PH-Fuse3 contains a specialized triple bonded designer creatine formula engineered to force an intense ATP release. Tri-Creatine Malate is a creatine salt that is formed through the bonding of malic acid and pure creatine. It is easily absorbed by the body and is involved as an intermediary in the Krebs cycle. Malic acid synergizes with the creatine to boost intercellular energy levels and the net bioactive potency of each respective compound.

Carnitine Creatinate Monohydrate is a specialized creatine substrate bonded with L-Carnitine. Carnitine is directly utilized in muscle cell mitochondria, which is actually considered by science as the “power house” of cells. Creatine Monohydrate has also been added in its undiluted form due to its highly researched ergogenic effects and proven efficacy. PH-Fuse3 produces a high level of cellular ATP, which may force dramatic increases in muscle cell hydration, torque and overall size and strength.

VasoPump3 – 6,000 mg
A powerful 3 way fusion of arginine compounds designed to dramatically and continuously increase Nitric Oxide (NO) production in muscle cells. Arginine is proven to dramatically increase NO levels in the body and is the direct precursor compound to the production of this Nobel Prize (1990) winning chemical. NO increases vasodilation and peripheral blood flow in muscle cells. Recent research also shows an increase in sarcomere production and in the total amount of muscle cells in the presence of NO. Extreme muscle pumps are reported in users and a greatly amplified anabolic effect is further experienced in the presence of ATP.

Due to its advanced design, VasoPump3 will force NO into your muscle cells using a unique and delicately precise process. Arginine Alpha-Ketoglutarate and Arginine Pyro-Glutamate are fast acting compounds shown to convert rapidly and efficiently into NO and synergize with the longer acting Arginine Hydrochloride. Arginine Hydrochloride contains a higher dose of pure L-Arginine per dose than the aforementioned two compounds and fuels production of NO directly. A precise combination of factors has been employed to induce extreme and continual conversion of MID CYCLE’s various L-Arginine substrates into NO. The focus of action for VasoPump3 is a site specific anabolic utilization by muscle cells. The ultra-high dose combination of arginine compounds utilized in MID CYCLE supercedes the dose of any other product currently on the market and is guaranteed to swell muscles with a solid and enduring gain.

Insulocine-XT – 2643 mg
Insulin is a potent anabolic compound that enhances the uptake of all ingested proteins, creatine, NO and ATP, glucose, amino acids, including vitamins and minerals. Insulin-XT is an extra strength insulin releasing secretagogue capable of enhancing the bodies natural production of this ultra-powerful nutrient shuttling, sugar regulating chemical. Insulin is a potent muscle cell volumizer on its own and the muscle pumps reported with its use are staggering. All compounds used in forming Insulocine-XT are proven to elicit massive insulin spikes with use and are synergistically combined to increase pancreatic secretion of this anabolic compound. When Insulocine-XT is precisely combined with PH-Fuse3 and VasoPump3, the effects of all compounds are radically amplified. This synergistic anabolic reaction is responsible for the enormously large muscle gains reported with use of MID CYCLE.

SRT – 875 mg
Fizogen employs its newly developed Substrate Regeneration Technology (SRT) compound to biologically recycle all of the metabolic byproducts of NO and creatine utilization. SRT contains specific precursor chemicals to Arginine and creatine that have been shown to turn on the body’s ability to produce these compounds naturally. SRT works synergistically with the byproducts of NO and creatine utilization in muscle cells to force further and continued NO and creatine production. SRT is developed in an exact ratio of bioactive components and designed to create a non-stop myotrophic pattern of production and dispersion of these compounds. SRT technology increases the net utilization of substrates and overall anabolic effect of NO and creatine in the body.

Phospho-MX – 535 mg
A high strength blend of phosphate compounds used to increase the retention and uptake of active ingredients in muscle cells. Phospho-MX’s precise blend of phosphate compounds and vital inter-bonded mineral cofactors enable optimal retention of active ingredients into muscle cells. Phospho-MX creates a virtual inexhaustible supply of intercellular energy by synergistically infusing with NO, creatine and SRT compounds. This prolongs anabolic activity in the body, which promotes revolutional and intense muscle growth.

Supplement Facts
Serving Size 2 Scoops
Servings Per Container 30
Amount Per Serving
Total Calories 32
Carbs 0mg
Protein 7,000mg
Calcium (as tricalcium phosphate and calcium carbonate) 750mg
Phosphorus (as Di-sodium phosphate, Di-Magnesium, phosphate, Di-potassium phosphate, Tri-calcium phosphate) 450mg
Magnesium (as Di-magnesium phosphate) 50mg
Sodium (as Di-sodium phosphate) 35mg
Potassium (as Di-potassium phosphate) 200mg
PH-Fuse3 (High-Tech Creatine Fusion) 10,000mg
Premium blend of Tri creatine malate, carnitine creatine monohydrate, creatine monohydrate
Insuloclne-XT (Pro-Insulin Secretogogue) 8,183mg
Contains L-arginine, L-taurine, fenugreek seed extract (4 -hydroxyisoleucine from trigonella foenum graecum L), banaba leaf extract (1% corosolic acid from langerstroemia speciosa), inositol hexaphosphoric acid (phytic acid), N-Beta-Alanyl-L-Histidine Tri-Chromic (chromium carnosinate)
SRT (Substrate Regeneration Technology) 955mg
Contains L-citrulline, betaine anhydrous, glycocyamine, b-nicotinamide adenine dinucleotide
Phospho-MX (Nutrient Retention Phosphate Blend) 535mg
Contains Di-sodium phosphate, Di-magnesium phosphate, Di-potassium phosphate, Tri-calcium phosphate

Other Ingredients:
Natural and artifical flavors, citric acid, silica, sucralose, food color FD&C red #40.

Directions:
As a dietary supplement, use(2) scoops daily. Workout days- Combine one scoop in 16oz. of water and drink 60-90 minutes prior to training. Combine one additional scoop in 16oz. of water and drink immediately following your workout. Non workout days- Combine one scoop with 16oz. of water and drink with a meal. Wait 4-6 hours and combine one additional scoop in 16oz. of water ang ingest with a meal. Drink at least 10-12 glasses of water each day during use of this product.


--------------------------------------------------------

[getfitdoc]

NOexplode gave me a headache and made me feel sick all day...

not as bad as fizogen "blast"... that stuff made me feel really sick..

v-12 i liked..

but i've stopped using any of the fancy no2/creatine supps.. i'd rather just go natural..

just because my system is so sensative.

[athiktos]

Check this site out...it has user reviews for almost every supplement out there. See what they have to say but I dont believe that there is anything for you to worry about. When you enter the site on the left you will see "manufactures" click that and scroll to BSN. peace!

[athiktos]

http://www.1fast400.com/

[BiggerthanLavar]

NO Xplode gave me nasty diahrrea....I just can't take the stuff.

[Ponderosa]

NOExplode made me flip off my computer screen b/c i'm sick of hearing people ask if it works. if you have to ask, it probably doesn't work. it's shit. better for you to send me your money.

[solcraft]

NOExplode made me flip off my computer screen b/c i'm sick of hearing people ask if it works. if you have to ask, it probably doesn't work. it's shit. better for you to send me your money.

nuff said............

[Suareezay]

NOExplode made me flip off my computer screen b/c i'm sick of hearing people ask if it works.

best. post. ever.

[Ponderosa]

best. post. ever.

a quick true protein story: because i live in the land of pussy, things cost a lot more to ship. i don't care, i say, just send my tein and carbs ASAP, no matter the cost. anyway, TP and i had an exchange of emails and they're charging me state taxes (as usual) even though i am buying overseas. can you believe these guys were nice enough to waive my shipping fees altogether?! awesome, awesome company. fyi: they said they'll have an updated/modified website design before the end of december.

[Suareezay]

a quick true protein story: because i live in the land of pussy, things cost a lot more to ship. i don't care, i say, just send my tein and carbs ASAP, no matter the cost. anyway, TP and i had an exchange of emails and they're charging me state taxes (as usual) even though i am buying overseas. can you believe these guys were nice enough to waive my shipping fees altogether?! awesome, awesome company. fyi: they said they'll have an updated/modified website design before the end of december.

exactly why TP is the best. DoggCrapp and all those boys are the shit. Their protein and customer service is the best. Ive read from people all over the place that accidentally get extra protein sent to them, and when they tell TP about it they just let them keep it, or if they get the wrong thing sent to them they get to keep it as well as their original order.

all their products are top quality (their new website will display all the COAs for every product) and their customer service is unbeatable. Their prices are spot on as well.

I order from bulk nutrition as well, simply because the owners of my gym are friends with the...i guess the owner, or founder of BN. They are also located in my state, so everything i order gets here the next day even with the cheapest shipping.

[Ponderosa]

exactly why TP is the best. DoggCrapp and all those boys are the shit. Their protein and customer service is the best. Ive read from people all over the place that accidentally get extra protein sent to them, and when they tell TP about it they just let them keep it, or if they get the wrong thing sent to them they get to keep it as well as their original order.

all their products are top quality (their new website will display all the COAs for every product) and their customer service is unbeatable. Their prices are spot on as well.

I order from bulk nutrition as well, simply because the owners of my gym are friends with the...i guess the owner, or founder of BN. They are also located in my state, so everything i order gets here the next day even with the cheapest shipping.

cosigns

[SuPPLementJuNkY]

I Have Never Heard Of Any Negative Feedback From Anybody Using No Xplode And From Experience The Only Draw Back I Would Say There Is Is A Little Water Retention

[solcraft]

I Have Never Heard Of Any Negative Feedback From Anybody Using No Xplode And From Experience The Only Draw Back I Would Say There Is Is A Little Water Retention

i count three in this post alone.

[Ponderosa]

that's great. rack him.

[blackjack]

tastes like shit, gives me headaches, tastes like shit, no better than creatine mono. tastes like shit.